1. Cornea and Ocular Surface

1. A prospective randomized clinical trial comparing femtosecond-laser–assisted versus mechanical keratoplasty outcomes in keratoconus patients: visual acuity and graft survival analysis

2. A cross-sectional observational study of tear film osmolarity and inflammatory cytokine profiles in dry eye disease using tear collection and multiplex ELISA

3. An in vitro laboratory assessment of antimicrobial efficacy of collagen-based corneal bandage lenses against Pseudomonas aeruginosa biofilms

4. A retrospective cohort analysis of pterygium recurrence rates following conjunctival autograft versus amniotic membrane graft: a 2-year follow-up

5. A case-control evaluation of meibomian gland dropout by meibography in patients with ocular rosacea versus controls

6. A prospective interventional study of platelet-rich plasma eye drops on epithelial healing time after photorefractive keratectomy

7. A methodological validation of in vivo confocal microscopy for assessment of corneal nerve fiber density in diabetic neuropathy

8. A systematic review and meta-analysis of limbal stem cell transplantation techniques for treatment of ocular surface chemical burns

9. An in silico docking and in vitro assessment of novel small molecules targeting matrix metalloproteinases in corneal ulcer healing

10. A narrative review of advances in amniotic membrane preservation methods and their clinical applications in ocular surface reconstruction

2. Cataract and Lens

1. A prospective double-blind randomized trial of blue-light–filtering versus standard intraocular lenses: impact on contrast sensitivity and visual quality

2. A retrospective cohort study of posterior capsular opacification rates and Nd:YAG capsulotomy timing following hydrophobic versus hydrophilic acrylic IOL implantation

3. An in vitro analysis of acrylic versus silicone IOL glistenings using light microscopy and quantification software

4. A case-control evaluation of intraoperative complications in femtosecond-laser–assisted cataract surgery versus conventional phacoemulsification

5. A prospective observational study of visual acuity and higher-order aberrations after trifocal versus extended-depth-of-focus IOL implantation

6. A methodological validation of lens opacity classification using swept-source OCT imaging compared to LOCS III grading

7. A randomized clinical trial of intracameral versus topical antibiotic prophylaxis in preventing postoperative endophthalmitis after cataract surgery

8. A systematic review and meta-analysis of systemic risk factors (diabetes, hypertension) influencing cataract progression rates

9. An in silico predictive modeling of capsular bag dynamics for accommodating IOL design optimization

10. A narrative review of emerging multifocal IOL technologies: visual outcomes and patient satisfaction

3. Glaucoma

1. A prospective randomized trial comparing trabeculectomy with mitomycin C versus XEN gel stent implantation: IOP reduction and complication analysis

2. A cross-sectional analytical study of retinal nerve fiber layer thickness by spectral-domain OCT in ocular hypertensive versus early glaucoma eyes

3. An in vitro flow chamber experiment assessing antifibrotic agents on conjunctival fibroblast proliferation relevant to glaucoma surgery success

4. A retrospective cohort analysis of selective laser trabeculoplasty efficacy and duration of IOP control in primary open-angle glaucoma

5. A case-control evaluation of corneal hysteresis measurements as predictors of visual field progression in normal-tension glaucoma

6. A prospective observational study of adherence patterns and barriers in patients on topical prostaglandin therapy using electronic monitoring

7. A methodological validation of telemetric IOP sensors versus Goldmann applanation tonometry in ambulatory glaucoma patients

8. A systematic review and meta-analysis of neuroprotective agents in slowing retinal ganglion cell loss in animal glaucoma models

9. An in silico modeling study of aqueous humor dynamics in micro-invasive glaucoma surgery devices

10. A narrative review of gene therapy approaches for neuroregeneration in glaucoma

4. Retina and Vitreous

1. A prospective randomized trial of monthly versus treat-and-extend anti-VEGF dosing regimens in diabetic macular edema: BCVA and CRT outcomes

2. A cross-sectional study of choroidal thickness variations in central serous chorioretinopathy using enhanced-depth imaging OCT

3. An in vitro assessment of vitreous substitutes’ biodegradation and biocompatibility in rabbit eye models

4. A retrospective analysis of idiopathic epiretinal membrane surgical outcomes comparing 27-gauge versus 25-gauge vitrectomy systems

5. A case-control evaluation of fundus autofluorescence patterns in Stargardt disease versus age-related macular degeneration

6. A prospective observational study of microaneurysm turnover by OCT angiography as a biomarker for progression in diabetic retinopathy

7. A methodological comparison of wide-field fundus photography versus ultrawide-field imaging in detection of peripheral retinal neovascularization

8. A systematic review and meta-analysis of subthreshold micropulse laser therapy efficacy in chronic central serous chorioretinopathy

9. An in silico drug release kinetics modeling for sustained-release intravitreal corticosteroid implants

10. A narrative review of emerging gene-editing therapies for inherited retinal dystrophies

5. Pediatric Ophthalmology and Strabismus

1. A prospective cohort study of amblyopia treatment outcomes: patching versus binocular game-based therapy in children aged 4–7 years

2. A cross-sectional screening program evaluation of retinopathy of prematurity incidence and risk factors in a tertiary neonatal ICU

3. An in vitro evaluation of viscoelastic agents for pediatric cataract surgery: endothelial cell safety and viscoelastic properties

4. A retrospective cohort study of surgical outcomes and recurrence rates in intermittent exotropia correction using bilateral lateral rectus recession

5. A case-control assessment of axial length and corneal curvature changes in pediatric glaucoma patients versus controls

6. A prospective observational study of tear film parameters in vernal keratoconjunctivitis–affected children using noninvasive tear breakup time

7. A methodological validation of handheld OCT for optic nerve head evaluation in neonates at risk of hypoxic injury

8. A systematic review of outcomes and complications of adjustable suture techniques in pediatric strabismus surgery

9. An in silico biomechanical modeling of extraocular muscle dynamics in Duane syndrome

10. A narrative review of advances in amblyopia neuroplasticity research and novel therapeutic modalities

6. Neuro-Ophthalmology and Ocular Motility

1. A prospective observational study of visual field restoration using microperimetry training in non-arteritic anterior ischemic optic neuropathy

2. A cross-sectional evaluation of retinal ganglion cell complex thickness in optic neuritis patients using spectral-domain OCT

3. An in vitro assay of autoantibody-mediated ganglioside binding in Miller Fisher syndrome patient sera

4. A retrospective cohort analysis of surgical outcomes in third-nerve palsy strabismus correction: muscle transposition versus recession–resection

5. A case-control study of contrast sensitivity and color vision defects in multiple sclerosis patients with versus without optic neuritis history

6. A methodological validation of eye-tracking technology for quantifying nystagmus intensity and waveform characteristics

7. A systematic review of diagnostic accuracy of visual evoked potentials in demyelinating versus compressive optic neuropathies

8. An in silico electrophysiological modeling of oculomotor nerve conduction velocity changes in diabetic neuropathy

9. A pilot experimental study of botulinum toxin injection patterns guided by EMG for management of chronic abductor palsy

10. A narrative review of emerging biomarkers for early detection of glaucoma-associated optic neuropathy

7. Oculoplastics, Orbit, and Lacrimal System

1. A prospective randomized trial of external versus endoscopic dacryocystorhinostomy: patency rates and patient-reported outcome measures

2. A cross-sectional imaging study of orbital fracture patterns using 3D CT reconstruction in maxillofacial trauma patients

3. An in vitro biomechanical testing of synthetic versus autologous graft materials for eyelid reconstruction

4. A retrospective cohort analysis of complication rates in ptosis correction: levator resection versus frontalis suspension

5. A case-control evaluation of tear film inflammatory markers in patients with punctal stenosis versus control subjects

6. A methodological validation of high-resolution ultrasound for lacrimal gland volumetry in thyroid eye disease

7. A systematic review of minimally invasive orbital decompression techniques for Graves’ ophthalmopathy

8. An in silico finite-element analysis of eyelid biomechanics in floppy eyelid syndrome

9. A pilot experimental study of platelet-rich fibrin injection in periocular rejuvenation: histological and clinical efficacy

10. A narrative review of 3D-printed prosthetic ocular implants: materials and long-term outcomes

8. Uveitis and Ocular Immunology

1. A prospective cohort study of aqueous humor cytokine profiles in HLA-B27–associated anterior uveitis versus idiopathic cases

2. A cross-sectional PCR-based detection of viral genomes (HSV, VZV, CMV) in aqueous samples of hypertensive anterior uveitis

3. An in vitro assay of peripheral blood mononuclear cell responses to tubercular antigens in presumed ocular tuberculosis

4. A retrospective analysis of immunosuppressive regimen efficacy and safety in juvenile idiopathic arthritis–associated uveitis

5. A case-control evaluation of serum angiotensin-converting enzyme and lysozyme levels in sarcoid versus non-sarcoid uveitis

6. A methodological validation of multiplex bead-based assays for simultaneous detection of multiple cytokines in vitreous fluid

7. A systematic review and meta-analysis of biological therapies (anti–TNF-α, anti–IL-6) in refractory non-infectious uveitis

8. An in silico network analysis of cytokine–chemokine interactions in ocular inflammatory pathways

9. A pilot experimental study of local sustained-release corticosteroid implants in chronic macular edema secondary to uveitis

10. A narrative review of emerging immunomodulatory targets in ocular autoimmune diseases

9. Refractive Surgery and Vision Correction

1. A prospective randomized trial comparing visual outcomes of LASIK versus SMILE in low-to-moderate myopia: aberration profiling and patient satisfaction

2. A cross-sectional survey of dry eye incidence and tear film changes following PRK using noninvasive break-up time and Schirmer’s test

3. An in vitro evaluation of corneal flap adhesion strength in femtosecond versus microkeratome LASIK

4. A retrospective cohort study of retreatment rates and corneal biomechanics after wavefront-guided versus topography-guided LASIK

5. A case-control assessment of night vision disturbances in monovision versus blended-vision presbyopic correction strategies

6. A methodological validation of iris registration accuracy in modern excimer laser platforms for customized ablations

7. A systematic review of outcomes and complications in phakic intraocular lens implantation for high myopia

8. An in silico ablation profile simulation study for optimization of refractive surgery nomograms

9. A pilot clinical trial of corneal collagen cross-linking combined with PRK for keratoconus management: safety and efficacy

10. A narrative review of emerging corneal inlay technologies for presbyopia correction

10. Recent Advances in Ophthalmology

1. A scoping review of AI-driven deep learning algorithms for automated detection of diabetic retinopathy in fundus photography

2. A prospective pilot study of gene therapy using adeno-associated viral vectors for Leber congenital amaurosis: safety and efficacy endpoints

3. A methodological assessment of handheld OCT angiography for bedside evaluation of retinal vascular disorders

4. An in vitro validation of nanoemulsion-based eye drop formulations for enhanced ocular drug delivery

5. An in silico systems biology analysis of signaling pathways in retinal degeneration for identification of therapeutic targets

6. A randomized clinical trial of transpalpebral electrical stimulation versus sham for neuroprotection in glaucoma suspects

7. A systematic review of emerging retinal prosthesis devices: visual outcomes and quality-of-life impact

8. A pilot experimental study of 3D bioprinted corneal stroma equivalents for transplantation research

9. A retrospective data-mining analysis of electronic health record big data for predicting ocular disease progression using machine learning

10. A narrative review of CRISPR-based gene-editing applications for inherited retinal disorders