Pediatric Neurology Thesis Topics

Pediatric Neurology Thesis Topics

Pediatric Neurology deals with disorders of the brain, spinal cord, peripheral nerves and neuromuscular systems in infants, children and adolescents. This page provides 100 detailed Pediatric Neurology thesis topics suitable for DM Pediatric Neurology residents in India and trainees in GCC countries (Saudi Arabia, UAE, Qatar, Oman, Kuwait, Bahrain), including Arab Board Neurology programmes.

Optimised for searches like pediatric neurology thesis topics, DM pediatric neurology dissertation topics India, GCC pediatric neurology research ideas, Arab Board neurology project titles, pediatric epilepsy thesis topics. All titles are **practical, clinical, comparative, observational or cross-sectional**, and feasible in Indian & GCC pediatric neurology departments.

1. Pediatric Epilepsy and Seizure Disorders

Comparative study of levetiracetam versus valproate as first-line therapy for generalized seizures in children. Evaluates seizure control, side-effect profile, behavioral changes and quality-of-life outcomes.
Observational study of drug-resistant epilepsy in children attending a tertiary pediatric neurology clinic. Reviews seizure types, etiological spectrum, imaging abnormalities and response to polytherapy.
Cross sectional EEG–clinical correlation analysis in new-onset seizure disorders in children. Explores predictive value of EEG patterns for recurrence and treatment planning.
Comparative study of ketogenic diet versus modified Atkins diet in children with refractory epilepsy. Examines seizure reduction, tolerability, nutritional changes and caregiver adherence.
Observational study of febrile seizures and predictors of recurrence in infants and young children. Evaluates family history, fever characteristics, developmental milestones and EEG findings.
Cross sectional analysis of seizure semiology and etiological trends in infants under one year of age. Identifies structural, metabolic and genetic causes common in Indian and GCC populations.
Comparative study of focal epilepsy outcomes in children with normal versus abnormal MRI findings. Measures seizure remission, medication requirement and neurodevelopmental impact.
Observational study of SUDEP risk factors in pediatric epilepsy. Reviews nocturnal seizures, uncontrolled epilepsy and medication adherence patterns.
Cross sectional study of adherence to anti-seizure medication and barriers faced by caregivers. Assesses socioeconomic, cultural and system-level gaps in India and GCC.
Comparative study of long-term cognitive outcomes in children with idiopathic versus symptomatic epilepsy. Evaluates school performance, memory and attention deficits on standardized scales.

2. Neurodevelopmental Disorders and Behavioral Neurology

Cross sectional analysis of global developmental delay etiologies in children presenting to a tertiary neurology clinic. Evaluates contributions of genetic, metabolic, perinatal and acquired causes.
Observational study of autism spectrum disorder profiles in Indian and GCC pediatric populations. Reviews early signs, comorbidities, diagnostic delays and response to therapy.
Comparative study of ADHD symptom severity in children with and without perinatal complications. Explores associations with prematurity, birth asphyxia and neonatal ICU stay.
Cross sectional study of learning disorders in school-aged children referred for neurological evaluation. Uses standardized educational and cognitive assessments to identify subtypes.
Observational study of regression syndromes in early childhood. Identifies neurodegenerative, epileptic and metabolic causes of developmental regression.
Comparative study of sleep disturbances in children with autism versus typically developing peers. Evaluates insomnia, restless sleep, melatonin use and behavioral interventions.
Cross sectional analysis of behavioral comorbidities in children with chronic neurological illnesses. Includes epilepsy, cerebral palsy and neuromuscular disorders.
Observational study of early developmental outcomes in high-risk infants discharged from NICU. Uses milestone charts, neurological exam and Bayley scales.
Comparative study of parent-reported versus clinician-assessed developmental delays. Evaluates accuracy of parental screening in low-resource settings.
Cross sectional study of screen-time exposure and its association with speech delay in toddlers. Captures duration, content type and socio-behavioral outcomes.

3. Neurometabolic and Neurogenetic Disorders

Observational study of leukodystrophy patterns in children undergoing MRI-based evaluation. Correlates imaging signatures with genetic confirmation where available.
Comparative study of outcomes in treated versus untreated congenital hypothyroidism detected on newborn screening. Reviews neurocognitive outcomes, growth and school performance.
Cross sectional analysis of mitochondrial disorders presenting to pediatric neurology services. Studies clinical spectrum, metabolic markers, and MRI findings.
Observational study of lysosomal storage disorders and time to diagnosis. Evaluates triggers for suspicion, diagnostic delays and caregiver experiences.
Comparative study of MRI brain patterns in metabolic versus hypoxic neurological injury. Helps differentiate treatable metabolic causes from irreversible damage.
Cross sectional study of Wilson disease in children presenting with neurological symptoms. Assesses Kayser–Fleischer rings, ceruloplasmin levels and MRI changes.
Observational study of neuroregression cases in resource-limited settings. Studies diagnostic algorithms used before advanced genetic testing availability.
Comparative study of next-generation sequencing versus targeted testing for pediatric neurogenetic disorders. Evaluates diagnostic yield, cost and turnaround time.
Cross sectional analysis of consanguinity and prevalence of neurogenetic disorders in GCC. Provides population-specific insights into inherited neurological disease.
Observational study of neuroimaging patterns in inborn errors of metabolism presenting with acute encephalopathy. Supports early differentiation of metabolic crises.

4. Neuromuscular Disorders

Observational study of Duchenne muscular dystrophy progression in children attending pediatric neurology clinics. Tracks motor milestones, respiratory decline and steroid therapy response.
Comparative study of corticosteroid regimens (daily vs intermittent) in Duchenne muscular dystrophy. Measures functional scores, adverse effects and quality of life.
Cross sectional analysis of nerve conduction abnormalities in children with suspected peripheral neuropathy. Identifies demyelinating vs axonal patterns and links them to clinical severity.
Observational study of spinal muscular atrophy presentation and outcomes in treated and untreated cohorts. Includes severity scoring, respiratory outcomes and need for supportive care.
Comparative study of EMG findings in myopathies versus neuropathies in pediatric patients. Helps refine diagnostic pathways in resource-limited electrophysiology units.
Cross sectional study of congenital myasthenic syndromes in Indian and GCC pediatric populations. Evaluates clinical variability and treatment response.
Observational study of nutritional and metabolic contributors to neuromuscular weakness in children. Includes vitamin deficiencies, thyroid dysfunction and electrolytes.
Comparative study of physiotherapy-intensive rehabilitation versus standard care in neuromuscular disorders. Measures functional gains, fatigue and mobility improvements.
Cross sectional analysis of respiratory function impairment in children with neuromuscular diseases. Includes spirometry trends and need for assisted ventilation.
Observational study of quality-of-life in caregivers of children with progressive neuromuscular disorders. Explores emotional, social and financial domains.

5. Pediatric Stroke and Cerebrovascular Disorders

Observational study of arterial ischemic stroke in children and associated risk factors. Includes cardiac disorders, infections, vasculitis and prothrombotic states.
Comparative study of MRI versus CT in early diagnosis of pediatric stroke. Examines sensitivity, timing and impact on treatment decisions.
Cross sectional analysis of cerebral venous sinus thrombosis in children. Studies predisposing factors, imaging patterns and clinical outcomes.
Observational study of moyamoya disease in pediatric neurology clinics. Reviews presentation, angiographic staging and surgical referral outcomes.
Comparative study of thrombotic versus hemorrhagic pediatric strokes. Measures neurological deficits, hospital stay and functional recovery.
Cross sectional study of stroke mimic conditions in children. Includes migraine variants, seizures, metabolic derangements and demyelination.
Observational study of long-term outcomes in children following perinatal stroke. Evaluates motor deficits, cognition and risk of later epilepsy.
Comparative study of rehabilitation intensity in functional recovery after pediatric stroke. Measures motor scores, speech outcomes and school reintegration.
Cross sectional analysis of vascular imaging techniques used for pediatric stroke evaluation. Reviews MRA, CTA and Doppler findings.
Observational study of post-stroke epilepsy in children. Identifies risk factors, seizure types and response to therapy.

6. Pediatric Neuroinfectious Disorders

Observational study of acute bacterial meningitis in children presenting to tertiary hospitals. Evaluates presenting features, CSF profile, complications and neurodevelopmental outcome.
Comparative study of viral versus bacterial encephalitis in children. Compares clinical presentation, imaging abnormalities and recovery patterns.
Cross sectional analysis of tuberculosis meningitis stages at diagnosis in Indian and GCC pediatric populations. Highlights delays, imaging patterns and predictors of neurological sequelae.
Observational study of neurocysticercosis in children. Includes seizure patterns, imaging characteristics and treatment response.
Comparative study of CSF PCR testing versus conventional microscopy/culture in pediatric CNS infections. Evaluates diagnostic yield and turnaround time.
Cross sectional study of dengue-related neurological complications in children. Reviews encephalopathy, stroke, demyelination and recovery.
Observational study of long-term cognitive impairment following CNS infections in childhood. Includes memory, attention and school performance scores.
Comparative study of adjunctive steroid therapy in meningitis versus encephalitis. Measures time to recovery and complication rates.
Cross sectional study of antimicrobial resistance patterns in pediatric CNS infections. Helps optimize empirical therapy protocols.
Observational study of seizures in acute CNS infections and predictors of recurrence. Differentiates acute symptomatic seizures from epilepsy risk.

7. Autoimmune and Neuroimmunology Disorders

Observational study of Guillain–Barré syndrome in children admitted to neurology services. Examines clinical subtypes, electrophysiology patterns and recovery timelines.
Comparative study of IVIG versus plasmapheresis in treating pediatric Guillain–Barré syndrome where both are available. Evaluates motor recovery, autonomic instability and complication rates.
Cross sectional analysis of pediatric acute disseminated encephalomyelitis (ADEM) and its triggers. Includes infection, vaccination and autoimmune markers.
Observational study of autoimmune encephalitis in children including antibody profiles. Reviews clinical presentation, MRI changes and response to immunotherapy.
Comparative study of monophasic versus recurrent demyelinating disorders in children. Measures disability progression, imaging predictors and relapse risk.
Cross sectional analysis of CSF inflammatory markers in autoimmune neurological diseases. Helps differentiate between infectious and autoimmune pathology.
Observational study of neuromyelitis optica spectrum disorders in pediatric patients. Reviews aquaporin-4 and MOG antibody patterns in India and GCC.
Comparative study of MRI lesion evolution in autoimmune demyelination following steroid versus IVIG therapy. Studies radiological improvement and clinical correlation.
Cross sectional analysis of autoimmune movement disorders in children. Includes tics, chorea and dystonia with immune triggers.
Observational study of long-term outcomes in pediatric autoimmune neurological diseases managed with immunomodulators. Includes relapse rates, disability scores and medication toxicity.

8. Neurological Emergencies and Neurocritical Care

Observational study of pediatric status epilepticus presentations and emergency management outcomes. Includes time-to-medication, recurrence risk and ICU requirement.
Comparative study of EEG-guided versus clinical-assessment-guided management in refractory status epilepticus. Measures seizure suppression, sedation need and ICU stay.
Cross sectional analysis of raised intracranial pressure presentations in children. Includes imaging predictors, optic nerve sheath diameter and outcome.
Observational study of acute flaccid paralysis in pediatric neurology services. Differentiates GBS, TM, viral causes and spinal cord lesions.
Comparative study of hypertonic saline versus mannitol in emergency management of raised intracranial pressure. Assesses neurological recovery and need for ventilation.
Cross sectional analysis of PICU admissions for neurological emergencies. Categorizes seizures, meningitis, metabolic crises and stroke.
Observational study of outcomes after pediatric neurocritical illness requiring mechanical ventilation. Assesses prognosis based on diagnosis, ventilation duration and complications.
Comparative study of early versus delayed imaging in acute neurological emergencies. Measures diagnostic yield and impact on treatment timelines.
Cross sectional study of electrolyte abnormalities in children presenting with acute encephalopathy. Includes sodium, calcium and glucose-related symptoms.
Observational study of in-hospital delays in pediatric neurological emergency care. Measures time from triage to imaging, lumbar puncture and treatment initiation.

9. Pediatric Headache, Movement Disorders and Sleep Neurology

Cross sectional analysis of migraine triggers and disability in school-aged children. Uses validated pediatric headache disability scores and lifestyle correlation.
Comparative study of cognitive behavioral therapy versus pharmacotherapy in pediatric migraine. Measures attack reduction, school absenteeism and sleep quality.
Observational study of tic disorders in children and association with ADHD and anxiety. Reviews severity grading and treatment response.
Cross sectional analysis of dystonia and chorea etiology in pediatric neurology clinics. Identifies autoimmune, genetic and secondary causes.
Observational study of sleep disorders in children with neurological illnesses. Includes insomnia, sleep apnea and parasomnias.
Comparative study of melatonin versus behavioral therapy for sleep onset problems in children. Measures latency, awakenings and caregiver satisfaction.
Cross sectional analysis of chronic daily headache patterns in adolescents. Includes medication overuse, stress triggers and academic correlation.
Observational study of movement disorder emergencies in pediatric neurology. Covers dystonic storms, status choreicus and acute onset tics.
Comparative study of dopaminergic therapy response in pediatric parkinsonism mimics. Includes Wilson disease, metabolic causes and genetic variants.
Cross sectional analysis of sleep quality in adolescents with epilepsy. Evaluates seizure frequency, medication effects and psychiatric comorbidities.

10. Long-Term Outcomes, Rehabilitation and Quality of Life

Observational study of neurodevelopmental outcomes in children after severe neurologic illness. Reviews cognitive, motor and behavioral domains using standardized tools.
Cross sectional analysis of school reintegration challenges in children with chronic neurological disorders. Assesses absenteeism, learning support and psychosocial barriers.
Comparative study of intensive physiotherapy versus standard rehabilitation in children with hemiparesis. Measures functional improvement and quality-of-life scores.
Observational study of caregiver burden in families caring for children with chronic neurologic disabilities. Examines emotional strain, financial challenges and coping strategies.
Cross sectional study of cognitive function in long-term epilepsy survivors. Uses memory and executive-function tests.
Observational study of mental health issues in adolescents with chronic neurological disorders. Includes depression, anxiety and self-esteem measures.
Comparative study of tele-neurology follow-up versus in-person care for stable pediatric neurology patients. Measures satisfaction, adherence, cost savings and clinical stability.
Cross sectional analysis of health-related quality-of-life in children with neuromuscular disorders. Includes mobility, self-care, social participation and pain.
Observational study of chronic pain syndromes in pediatric neurology clinics. Identifies headache, neuropathic pain, fibromyalgia and somatic symptoms.
Comparative study of multidisciplinary versus single-specialty rehabilitation in children with complex neurological disabilities. Measures functional gains, caregiver feedback and long-term outcomes.
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