Neurosurgery Thesis Topics

Neurosurgery Thesis Topics

Neurosurgery encompasses cranial, spinal, peripheral nerve and neurocritical care disorders, including trauma, tumors, vascular lesions, functional diseases and pediatric neurosurgery. This page provides 100 detailed and practical Neurosurgery thesis topics for M.Ch Neurosurgery residents in India and trainees preparing for Gulf Cooperation Council (UAE, Qatar, Oman, Kuwait, Bahrain, Saudi Arabia) boards, including Arab Board Neurosurgery and Saudi Commission.

These topics are SEO-optimized for Neurosurgery thesis topics, M.Ch neurosurgery dissertation topics India, GCC neurosurgery research projects, Arab Board neurosurgery research ideas, brain tumor research topics, spine surgery studies. Most titles are structured as comparative studies, observational cohorts, and cross-sectional analyses that are feasible in tertiary neurosurgical centers.

1. Neurotrauma and Emergency Neurosurgery

Comparative study of early decompressive craniectomy versus initial medical management in traumatic brain injury with refractory intracranial hypertension. This study evaluates mortality, neurological recovery and complications at 6 months.
Observational study of clinical and radiological predictors of poor outcome in acute subdural hematoma managed surgically. The project analyzes midline shift, GCS score, timing of intervention and postoperative recovery.
Cross sectional analysis of road traffic accident–related head injuries in Indian and GCC populations. The thesis reviews demographic patterns, helmet use and preventable risk factors.
Comparative study of endoscopic versus open evacuation of acute intracerebral hemorrhage where both modalities are practiced. Outcome metrics include hematoma clearance, rebleeding and functional independence.
Observational study of seizures and post-traumatic epilepsy after moderate-to-severe head injury. The study correlates lesion type, surgery, and antiepileptic drug prophylaxis with recurrence risk.
Comparative study of outcomes in early versus delayed surgery for traumatic acute extradural hematoma. The project evaluates operative timing, pupillary reaction and postoperative neurological recovery.
Cross sectional analysis of anticoagulant-associated traumatic intracranial hemorrhage and reversal strategies used. The thesis analyzes outcomes after vitamin K, PCC, and newer reversal agents.
Observational study of traumatic brain injury–related diffuse axonal injury diagnosed by magnetic resonance imaging. This work evaluates MRI grading, neurocognitive outcomes and disability.
Comparative study of ICP monitoring versus no ICP monitoring in severe traumatic brain injury where both practices coexist. Outcome parameters include ICU stay, mortality and quality of recovery.
Cross sectional analysis of penetrating head injuries: clinical profile, infection risk and neurosurgical outcomes. The project evaluates mechanism of injury, foreign bodies and postoperative morbidity.

2. Supratentorial Brain Tumor Neurosurgery

Comparative study of awake craniotomy versus general anesthesia for resection of gliomas in eloquent cortex. This thesis evaluates extent of resection, language deficits and seizure outcomes.
Observational study of clinical and radiological predictors of survival in high-grade gliomas. The project reviews tumor volume, edema, MGMT status (if available) and adjuvant therapy.
Cross sectional analysis of seizure control in patients undergoing tumor resection for supratentorial gliomas. The study evaluates seizure-free rates, antiepileptic drug requirement and tumor grade.
Comparative study of neuronavigation-assisted glioma resection versus conventional microsurgery. Parameters assessed include residual tumor volume and postoperative neurological deficits.
Observational study of cognitive outcomes after resection of frontal lobe tumors. The project examines executive function, attention and behavioral changes post-surgery.
Cross sectional analysis of meningioma subtypes and recurrence patterns after surgery. The thesis correlates histology, surgical grading and follow-up imaging findings.
Comparative study of seizure outcomes between low-grade and high-grade glioma patients undergoing surgery. The project evaluates preoperative EEG, tumor location and recurrence.
Observational study of quality of life in patients undergoing resection for primary brain tumors. The project assesses functional scales, anxiety, and long-term independence.
Cross sectional analysis of incidental brain tumors detected on imaging and neurosurgical management strategies. The thesis reviews follow-up patterns, biopsy indications, and surgical timing.
Comparative study of early versus delayed postoperative radiotherapy in high-grade gliomas. Outcomes assessed include survival, neurological status, and recurrence patterns.

3. Posterior Fossa and Skull Base Neurosurgery

Comparative study of retrosigmoid versus translabyrinthine approach for vestibular schwannoma where both approaches exist. This thesis evaluates hearing preservation, facial nerve outcomes and complications.
Observational study of cerebellopontine angle tumors and predictors of postoperative cranial nerve deficits. The project evaluates tumor size, adherence, and intraoperative findings.
Cross sectional analysis of posterior fossa meningiomas and surgical outcomes. The thesis assesses extent of resection, recurrence and complications like CSF leak.
Comparative study of endoscopic-assisted versus standard microsurgical resection of skull base tumors. Outcomes include visualization, resection completeness and safety.
Observational study of brainstem cavernomas and neurological recovery after surgery. The project evaluates functional outcome and radiological changes.
Cross sectional analysis of Chiari malformation surgical outcomes in adult and pediatric groups. This thesis evaluates syrinx resolution, headache improvement and neurological recovery.
Comparative study of different dural closure techniques in posterior fossa surgery to reduce cerebrospinal fluid leak. The project assesses graft materials, watertight closure and reoperation rates.
Observational study of postoperative cranial nerve palsies after posterior fossa surgery. The project analyzes risk factors and recovery timelines.
Cross sectional analysis of foramen magnum tumors and predictors of surgical morbidity. The thesis evaluates tumor pathology, approach and neurological deficits.
Comparative study of MRI-based brainstem compression indices and clinical outcomes in posterior fossa lesions. The research correlates imaging severity with neurological presentation.

4. Cerebrovascular Neurosurgery

Comparative study of microsurgical clipping versus endovascular coiling in ruptured anterior circulation aneurysms where both services are available. Outcomes include rebleeding, vasospasm and functional recovery.
Observational study of vasospasm detection using transcranial Doppler in subarachnoid hemorrhage. The project evaluates early identification and progression.
Cross sectional analysis of arteriovenous malformation presentations and Spetzler-Martin grading correlation with surgical outcomes. The thesis assesses hemorrhage risk, resection success and complications.
Comparative study of early versus delayed surgery for ruptured aneurysms. Outcomes measured include operative morbidity, rebleeding and ICU duration.
Observational study of Moyamoya disease in Indian and GCC populations. The project evaluates angiographic classification, clinical features and surgical outcomes.
Cross sectional analysis of aneurysm morphology and risk of rupture using radiological scoring systems. The thesis evaluates dome-to-neck ratio, size and irregularity.
Comparative study of bypass surgery outcomes in complex aneurysms versus AVM cases. The project evaluates graft patency and neurological status.
Observational study of intracranial arterial dissections and neurosurgical intervention outcomes. The research assesses presentation, imaging and prognosis.
Cross sectional analysis of cerebral venous sinus thrombosis requiring neurosurgical decompression. The thesis reviews imaging patterns, ICP levels and recovery.
Comparative study of vasospasm management protocols in aneurysmal subarachnoid hemorrhage. Outcomes measured include delayed cerebral ischemia and neurological status.

5. Spine Surgery – Degenerative and Instrumentation

Comparative study of posterior lumbar interbody fusion versus transforaminal lumbar interbody fusion in degenerative lumbar disease. The thesis measures fusion rates, disability scores and complications.
Observational study of clinical and radiological profile of cervical spondylotic myelopathy. The project assesses neurologic recovery and myelopathy grading.
Cross sectional analysis of lumbar canal stenosis and comparison of outcomes after open versus minimally invasive decompression. The study evaluates pain relief, mobility and hospital stay.
Comparative study of dynamic stabilization versus fusion for lumbar instability. Outcomes include adjacent segment disease, pain and mobility.
Observational study of postoperative complications after instrumented spine surgery. The project analyzes infection, implant failure and reoperation.
Cross sectional analysis of sagittal balance parameters in degenerative lumbar disease. The thesis evaluates alignment changes and functional outcomes.
Comparative study of cervical disc replacement versus anterior cervical discectomy and fusion. This research assesses range of motion and adjacent segment changes.
Observational study of vertebral fractures and neurologic decline in elderly patients. The project evaluates osteoporosis, imaging and surgical indications.
Cross sectional analysis of back pain disability and correlation with imaging severity. The thesis examines mismatch between symptoms and radiology.
Comparative study of early versus delayed mobilization after lumbar decompression. The study measures pain, gait and readmission rates.

6. Spine Tumor, Infection and Complex Deformity

Observational study of spinal metastasis and factors predicting neurological deterioration. The project examines tumor type, instability scores and decompression outcomes.
Comparative study of anterior versus posterior approaches in thoracolumbar spinal tuberculosis. Outcomes include correction, fusion and neurological improvement.
Cross sectional analysis of primary spinal tumors and surgical outcomes. The thesis differentiates schwannomas, meningiomas and rare lesions.
Observational study of pediatric scoliosis deformity correction and postoperative recovery. The project reviews degree of correction, complications and quality of life.
Comparative study of single-stage versus staged decompression in extensive spinal infection. Outcomes assessed include neurological recovery, blood loss and morbidity.
Cross sectional analysis of vertebral osteomyelitis and response to combined surgical and medical therapy. The thesis evaluates imaging improvement and inflammatory markers.
Observational study of postoperative spinal deformity in children treated for intramedullary tumors. The project assesses risk factors and functional outcome.
Comparative study of surgical versus non-surgical treatment for metastatic spinal cord compression when both pathways are used. The study evaluates ambulation and survival.
Cross sectional analysis of kyphotic deformity severity and neurological deficit correlation. The thesis examines radiology and functional impairment.
Observational study of rehabilitation outcomes after spinal tumor surgery. The project evaluates mobility, pain and independence.

7. Functional and Stereotactic Neurosurgery

Comparative study of deep brain stimulation for Parkinson’s disease using different target nuclei where possible. Outcomes include tremor control, dyskinesias and quality of life.
Observational study of epilepsy surgery outcomes in patients with medically refractory focal epilepsy. The project reviews seizure freedom, complications and neuropsychology.
Cross sectional analysis of radiofrequency ablation procedures for trigeminal neuralgia. The thesis examines pain relief duration and recurrence.
Comparative study of different imaging modalities for identifying seizure foci in epilepsy surgery evaluation. The study measures concordance with surgical findings.
Observational study of vagus nerve stimulation outcomes where available. The project assesses seizure reduction and quality-of-life improvement.
Cross sectional analysis of functional outcomes after stereotactic biopsy for deep-seated brain lesions. The thesis evaluates diagnostic yield and complication rates.
Comparative study of microvascular decompression versus percutaneous procedures for trigeminal neuralgia. Outcomes include pain relief durability and operative risks.
Observational study of chronic pain syndromes managed with spinal cord stimulation where services exist. The project evaluates pain scales, device complications and patient satisfaction.
Cross sectional analysis of movement disorder surgery candidates and preoperative workup quality. The thesis reviews levodopa challenge, imaging and neuropsychology.
Observational study of psychosocial impact in patients undergoing functional neurosurgery. The project examines mood, independence and social reintegration.

8. Pediatric Neurosurgery

Cross sectional analysis of congenital hydrocephalus and outcomes after ventriculoperitoneal shunting. The thesis evaluates complications, revision rates and developmental outcomes.
Observational study of neural tube defects and surgical outcomes in neonates and infants. The project examines infection, neurological recovery and hydrocephalus risk.
Comparative study of endoscopic third ventriculostomy versus shunt surgery in obstructive hydrocephalus. Outcomes include failure rate, need for reoperation and neurological improvement.
Cross sectional analysis of pediatric brain tumors and surgical resectability. The thesis reviews histology, location and survival.
Observational study of craniosynostosis surgery outcomes. The project evaluates cosmetic improvement, intracranial pressure and complications.
Comparative study of early versus delayed surgery in tethered cord syndrome. The research examines neurological recovery and urological outcomes.
Cross sectional analysis of pediatric traumatic brain injury and predictors of poor recovery. The thesis evaluates Glasgow Coma Scale, imaging and extracranial injuries.
Observational study of long-term outcomes after posterior fossa tumor surgery in children. The project assesses cerebellar dysfunction, cognitive deficits and recurrence.
Comparative study of minimally invasive versus open approaches in pediatric spinal dysraphism. Outcomes assessed include wound healing and neurological improvement.
Cross sectional analysis of epilepsy surgery outcomes in pediatric patients. The thesis evaluates seizure control and cognitive development.

9. Peripheral Nerve Surgery

Observational study of brachial plexus injuries and functional recovery after nerve grafting or nerve transfer. The project evaluates motor outcomes and electromyography.
Comparative study of carpal tunnel decompression under local versus regional anesthesia. Outcomes include pain relief, complications and return to work.
Cross sectional analysis of peripheral nerve sheath tumors and surgical outcomes. The thesis examines histology, recurrence and functional improvement.
Observational study of traumatic nerve injuries and prognostic factors influencing recovery. The project reviews timing of repair and nerve gap length.
Comparative study of neurolysis versus nerve grafting in chronic compressive neuropathies. Outcomes include symptom relief and electrophysiological improvement.
Cross sectional analysis of foot drop etiologies and surgical correction outcomes. The thesis examines peroneal nerve lesions and lumbar root involvement.
Observational study of nerve conduction recovery after repair of median and ulnar nerve injuries. The project evaluates functional recovery and sensory outcomes.
Comparative study of open versus endoscopic cubital tunnel release. Outcome measures include elbow pain, grip strength and recovery time.
Cross sectional analysis of peripheral nerve trauma in industrial workers in India and GCC. The thesis reviews mechanisms of injury, rehabilitation and socioeconomic impact.
Observational study of post-surgical neuropathic pain after peripheral nerve procedures. The project evaluates risk factors and therapy response.

10. Neurosurgery ICU Care and Postoperative Outcomes

Observational study of postoperative complications in neurosurgical intensive care units. The project evaluates infection, seizures, electrolyte abnormalities and respiratory complications.
Comparative study of early extubation versus delayed extubation protocols after elective cranial surgery. Outcomes include ICU stay, airway complications and recovery.
Cross sectional analysis of unplanned ICU readmissions after neurosurgery. The thesis examines risk factors such as bleeding, seizures and respiratory failure.
Observational study of postoperative meningitis and wound infections in neurosurgical patients. The project examines prophylaxis, CSF leak and pathogens.
Comparative study of early mobilization versus standard care after cranial surgery. The research evaluates functional recovery, delirium and length of stay.
Cross sectional analysis of electrolyte abnormalities in post-craniotomy patients. The thesis assesses sodium disturbances, seizures and consciousness level.
Observational study of delirium rates in the neurosurgical ICU. The project examines risk factors and outcomes.
Comparative study of enhanced recovery pathways versus conventional care in neurosurgery. Outcomes include pain, length of stay and complication rates.
Cross sectional analysis of unplanned reoperations after elective neurosurgery. The thesis identifies bleeding, infection and inadequate decompression.
Observational study of pain management protocols and opioid-sparing regimens in neurosurgical patients. The project evaluates analgesia effectiveness and side effects.
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