Infectious Diseases Thesis Topics
Infectious diseases involve the diagnosis, epidemiology, prevention and management of bacterial, viral, fungal and parasitic infections. This curated list provides 100 practical and research-ready Infectious Diseases thesis topics ideal for DM Infectious Diseases residents in India, as well as physicians preparing for Arab Board, Saudi Board, Oman Medical Specialty Board, and GCC residency programs. These topics are structured as observational, cross-sectional and comparative studies feasible in Indian tertiary hospitals and Gulf teaching institutions.
Whether you are searching for Infectious Diseases thesis topics, DM Infectious Diseases dissertation topics, GCC infection research projects, or Arab Board infectious diseases research ideas, these 10 subsections cover bacterial infections, viral diseases, HIV, tuberculosis, antimicrobial resistance, emerging infections and vaccine-preventable illnesses.
1. Bacterial Infections
Observational study on clinical spectrum, severity markers and outcomes in adults hospitalized with community-acquired pneumonia.
This study evaluates risk factors, radiologic patterns, biomarkers and predictors of respiratory failure.
Comparative assessment of outcomes in culture-positive versus culture-negative sepsis in a tertiary care hospital.
The project examines severity, organ dysfunction and survival differences between the two groups.
Cross-sectional study of clinical predictors of bacterial meningitis in adults presenting with acute febrile encephalopathy.
This research evaluates cerebrospinal fluid patterns, biomarkers and imaging correlations.
Study of risk factors and outcomes in patients with infective endocarditis, including patterns of valvular involvement and complications.
The thesis identifies microbial spectrum, embolic events and predictors of mortality.
Observational study of surgical site infections: incidence, risk factors and microbiologic profile.
This project evaluates contamination risks, organism distribution and prevention practices.
Study of bloodstream infections in hospitalised adults: microbial patterns and antibiotic resistance trends.
The research analyses Gram-positive versus Gram-negative infections and outcome predictors.
Cross-sectional analysis of Clostridioides difficile infection epidemiology in post-antibiotic diarrhoea.
The study identifies risk factors, recurrence patterns and complications.
Study of bacterial liver abscess: clinical features, imaging patterns and treatment outcomes.
This thesis evaluates therapeutic drainage success and microbiologic distribution.
Observational study of necrotizing fasciitis: early diagnostic signs, microbial profile and predictors of poor outcome.
The research examines delay in diagnosis, comorbidities and need for repeated debridement.
Study of osteomyelitis in adults: chronicity patterns, risk factors and response to antimicrobial therapy.
The thesis documents biofilm-associated infections and treatment challenges.
2. Tuberculosis (Pulmonary & Extrapulmonary)
Cross-sectional evaluation of diagnostic delays in pulmonary tuberculosis and associated sociodemographic determinants.
The study quantifies patient delay, system delay and their impact on disease severity.
Observational study of clinical and radiological predictors of drug-resistant tuberculosis.
The thesis examines risk factors, chest imaging patterns and microbiologic correlations.
Comparative analysis of treatment outcomes in patients receiving daily versus intermittent tuberculosis therapy.
This project evaluates adherence, sputum conversion and relapse rates.
Study of extrapulmonary tuberculosis presentations at a tertiary centre.
The research reviews lymph node, abdominal, pleural and central nervous system tuberculosis patterns.
Study of adverse drug reactions to anti-tuberculosis therapy and their impact on treatment interruption.
This project assesses hepatotoxicity, gastrointestinal intolerance and peripheral neuropathy.
Observational study of tuberculosis in diabetes mellitus: presentation, radiologic patterns and treatment outcomes.
The thesis explores bidirectional risk and poor glycaemic control associations.
Cross-sectional evaluation of latent tuberculosis infection screening in healthcare workers.
This research analyses positivity rates and occupational risk factors.
Study of relapse predictors in previously treated tuberculosis patients.
The project reviews adherence history, baseline bacillary load and comorbidities.
Study of tuberculosis-associated uveitis and ocular manifestations.
The thesis evaluates diagnostic criteria and treatment response.
Observational study of predictors of mortality in severe tuberculosis requiring hospitalisation.
This research evaluates respiratory failure, organ dysfunction and nutritional status.
3. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
Cross-sectional study of opportunistic infections in newly diagnosed HIV patients.
This study documents frequency of tuberculosis, candidiasis, Pneumocystis pneumonia and cryptococcal disease.
Observational study of immune reconstitution inflammatory syndrome incidence and predictors in patients initiating antiretroviral therapy.
The research examines baseline CD4 counts, viral loads and comorbidities.
Study of adherence patterns, barriers and facilitators to antiretroviral therapy among adults living with HIV.
This project assesses psychosocial factors influencing adherence.
Comparative analysis of metabolic complications between different antiretroviral therapy regimens.
The thesis evaluates dyslipidaemia, insulin resistance and anthropometric changes.
Study of neurocognitive impairment in HIV patients on long-term antiretroviral therapy.
This research uses cognitive screening tools to assess impairment patterns.
Observational study of cardiovascular risk markers in HIV-positive individuals.
The project examines inflammatory markers, lipid profiles and metabolic risk.
Study of mother-to-child transmission prevention program adherence and outcomes.
The thesis evaluates antenatal screening, antiretroviral prophylaxis and infant HIV testing.
Cross-sectional study of stigma, discrimination and mental health in people living with HIV.
This research evaluates depression, anxiety and social functioning.
Study of ART toxicity patterns leading to regimen change in HIV patients.
The thesis explores renal dysfunction, hypersensitivity reactions and neuropsychiatric effects.
Observational study of co-infection patterns of HIV with tuberculosis, hepatitis B and hepatitis C.
This project analyses prevalence, severity and treatment challenges.
4. Viral Infections
Study of dengue fever severity predictors in hospitalised adults.
The research examines warning signs, laboratory abnormalities and outcomes.
Cross-sectional evaluation of hepatitis B infection patterns, viral load distribution and fibrosis stage in adults.
This project assesses treatment eligibility and comorbidities.
Study of viral hepatitis C treatment outcomes after direct-acting antiviral therapy.
The thesis documents sustained virological response and adverse effects.
Observational study of influenza-related hospitalisations and predictors of severe outcomes.
This research evaluates vaccination status, age groups and chronic disease impact.
Study of chikungunya-associated chronic arthritis and long-term functional outcomes.
The project assesses symptom persistence and quality of life.
Cross-sectional study of varicella complications in adults and risk factors for severe disease.
The thesis evaluates pneumonitis and encephalitis risks.
Study of viral encephalitis: clinical profile and predictors of neurologic sequelae.
This research examines biomarkers and neuroimaging correlations.
Observational study of cytomegalovirus infection patterns in immunocompromised patients.
The study reviews reactivation risk and treatment response.
Study of measles outbreaks in adults: vaccination history, complications and outcomes.
This project analyses outbreaks in partially immunised populations.
Study of predictors of severe hand, foot and mouth disease during outbreaks.
The thesis evaluates disease progression and neurologic involvement.
5. Fungal Infections
Cross-sectional study of invasive candidiasis in hospitalised patients and risk factor analysis.
The research examines catheter use, antibiotic exposure and ICU stay.
Study of mucormycosis: clinical profile, risk factors and outcomes in diabetic and immunocompromised patients.
The thesis assesses severity markers and treatment success.
Observational study of pulmonary aspergillosis in chronic lung disease patients.
This project evaluates radiologic findings and serologic tests.
Study of antifungal resistance patterns in Candida and Aspergillus isolates.
The research highlights emerging resistance and treatment challenges.
Cross-sectional evaluation of dermatophytosis patterns and treatment outcomes.
This thesis assesses chronicity, recurrence and antifungal misuse.
Study of cryptococcal meningitis in immunocompromised patients.
This research evaluates CSF markers, treatment and neurologic outcomes.
Study of invasive fungal sinusitis: early diagnostic markers and surgical outcomes.
The thesis focuses on imaging patterns and survival.
Observational evaluation of histoplasmosis where prevalent.
The research assesses presentation, diagnostic methods and treatment.
Study of fungal bloodstream infections in intensive care units.
This thesis evaluates outcomes and antifungal strategies.
Study of risk factors for recurrent vaginal candidiasis in reproductive-aged women.
The research evaluates behavioural and clinical predictors.
6. Parasitic and Tropical Diseases
Study of malaria severity predictors and outcomes in hospitalised adults.
The project examines parasitemia levels, organ involvement and mortality risk factors.
Observational study of visceral leishmaniasis: clinical profile and treatment outcomes.
This thesis evaluates haematologic abnormalities and relapse rates.
Cross-sectional evaluation of intestinal parasitic infections in migrant populations.
The research assesses prevalence and socioeconomic determinants.
Study of filariasis-related chronic lymphoedema and quality-of-life impairment.
The project evaluates disability and functional limitations.
Study of enteric fever: antimicrobial resistance patterns and treatment outcomes.
This thesis evaluates relapse, complications and multidrug resistance.
Observational study of scrub typhus: clinical manifestations and complications.
The research evaluates organ dysfunction and outcomes.
Study of hydatid disease: diagnostic imaging patterns and surgical outcomes.
The project analyses cyst size, complications and recurrence.
Cross-sectional study of toxoplasmosis seroprevalence among immunocompromised adults.
The thesis examines associated clinical risk factors.
Study of dengue-malaria co-infection and its impact on severity.
The research evaluates overlapping clinical features and diagnostic challenges.
Study of strongyloidiasis in adults with immunosuppression.
This thesis assesses diagnostic delays and treatment outcomes.
7. Antimicrobial Resistance and Stewardship
Cross-sectional study of antimicrobial resistance patterns in common Gram-negative pathogens.
This project analyses ESBL, carbapenemase and multidrug resistance trends.
Study of inappropriate antimicrobial prescriptions in outpatient clinics and contributing factors.
The thesis evaluates common errors and knowledge gaps.
Observational study on antibiotic consumption metrics in hospital wards.
The research assesses utilisation patterns and stewardship targets.
Study of Clostridioides difficile infection incidence before and after stewardship interventions.
The project evaluates antimicrobial restriction impact.
Study of carbapenem-resistant Acinetobacter and their clinical outcomes.
This thesis assesses mortality predictors and treatment challenges.
Cross-sectional study of hand hygiene compliance among healthcare workers.
The research identifies barriers and compliance improvement opportunities.
Study of knowledge, attitudes and practices toward antibiotic stewardship among physicians.
This project evaluates understanding of resistance mechanisms and stewardship principles.
Observational study of antibiotic usage trends in intensive care units.
The thesis examines escalation, de-escalation and dosing practices.
Study of bacterial resistance development during prolonged hospitalisation.
This research evaluates colonisation patterns and transition to infection.
Study of environmental contamination and bacterial load in healthcare settings.
The thesis evaluates surface cultures, risk hotspots and cleaning practices.
8. COVID-19 and Emerging Infectious Diseases
Observational study of clinical predictors of severe COVID-19 in hospitalised adults.
The research evaluates risk factors, biomarkers and oxygen requirement.
Study of post-COVID complications and long-term sequelae in recovered patients.
The thesis evaluates respiratory, cardiovascular and neuropsychiatric outcomes.
Cross-sectional study of vaccination uptake and hesitancy in adults during COVID-19 campaigns.
This project assesses sociodemographic influences and barriers.
Study of multisystem inflammatory syndrome in adults following viral infections.
This research analyses clinical patterns and outcomes.
Study of secondary bacterial infections in COVID-19 patients receiving steroids.
The thesis evaluates infection profile and outcomes.
Observational study of antiviral therapy effectiveness in emerging viral infections.
This project reviews clinical improvement and safety.
Study of mucormycosis in post-COVID patients: risk factors and outcomes.
The thesis assesses complications and mortality predictors.
Cross-sectional analysis of healthcare worker infections during infectious disease outbreaks.
The project evaluates occupational exposure risks.
Study of viral mutation patterns and their association with disease severity where genomic testing is available.
This research analyses emerging strain characteristics.
Study of telemedicine usage patterns during infectious disease outbreaks.
The thesis evaluates access, satisfaction and barriers.
9. Hospital-Acquired and Device-Associated Infections
Study of catheter-associated urinary tract infections: risk factors, microbial profile and prevention practices.
The research evaluates device duration, organism spectrum and outcomes.
Observational study of ventilator-associated pneumonia in intensive care units.
This thesis assesses risk factors, pathogens and mortality predictors.
Study of central-line associated bloodstream infections and bundle compliance.
The project evaluates line maintenance practices and infection incidence.
Cross-sectional study of hospital environmental cultures and contamination hotspots.
This research identifies surfaces with high microbial load.
Study of antimicrobial prophylaxis appropriateness in surgical procedures.
The thesis evaluates timing, duration and agent selection adherence.
Study of infection control compliance in intensive care settings.
This project evaluates checklist adherence and outcome impact.
Observational study of nosocomial diarrhoea and microbial etiologies.
The thesis assesses Clostridioides difficile and non-infectious causes.
Study of bloodstream infections in patients with indwelling urinary catheters.
This research analyses microbial distribution and risk factors.
Study of hospital-acquired skin and soft tissue infections: risk patterns and outcomes.
The thesis evaluates high-risk wards and prevention practices.
Study of antibiotic escalation practices in intensive care units.
The project assesses appropriateness and stewardship alignment.
10. Infections in Immunocompromised Hosts
Study of febrile neutropenia in cancer patients: microbial profile and outcome predictors.
This thesis evaluates timing of fever, organism spectrum and risk scoring.
Cross-sectional analysis of infections in solid organ transplant recipients.
The project reviews early versus late infection patterns and outcomes.
Study of infection risks in patients on long-term corticosteroids or immunosuppressants.
The research evaluates infection types and preventive strategies.
Study of opportunistic infections in patients receiving biologic therapy.
This thesis examines tuberculosis, fungal infections and viral reactivation.
Observational study of cytomegalovirus disease in immunosuppressed adults.
The project evaluates risk factors, clinical manifestations and outcomes.
Study of invasive fungal infections in neutropenic adults.
The research evaluates diagnostic markers and treatment response.
Study of bloodstream infections in dialysis patients.
This thesis analyses access-related infections and risk reduction measures.
Cross-sectional evaluation of vaccination coverage in immunocompromised adults.
The project examines gaps in influenza, pneumococcal and hepatitis immunisation.
Study of post-transplant tuberculosis in high-burden countries.
The research evaluates presentation, latency and treatment challenges.
Study of recurrent infections in immunodeficiency syndromes.
This thesis assesses diagnostic patterns and management strategies.