1. Mood Disorders

1. A prospective cohort study of serum brain-derived neurotrophic factor (BDNF) levels and relapse rates in bipolar disorder patients on lithium maintenance therapy

2. A randomized double-blind trial comparing cognitive behavioral therapy versus interpersonal therapy in adults with major depressive disorder: remission rates and neuroticism scores

3. A cross-sectional analysis of HPA axis dysregulation using salivary cortisol profiles in untreated versus treated major depression

4. A retrospective cohort evaluation of treatment adherence and hospitalization frequency in patients with rapid-cycling bipolar disorder

5. An in vitro peripheral blood mononuclear cell cytokine assay in depressed patients before and after SSRI therapy: Th1/Th2 balance

6. A case-control genetic association study of CLOCK gene polymorphisms in seasonal affective disorder versus healthy controls

7. A methodological validation of the PHQ-9 scale translation into regional languages for depression screening in primary care

8. A systematic review and meta-analysis of ketamine infusion protocols for rapid antidepressant response in refractory depression

9. An in silico molecular docking study of novel antidepressant candidates targeting the serotonin transporter

10. A narrative review of emerging neurostimulation techniques (TMS, tDCS) in treatment-resistant mood disorders

2. Psychotic Disorders

1. A prospective observational study of white matter integrity changes on DTI-MRI in first-episode schizophrenia patients before and after antipsychotic treatment

2. A randomized controlled trial of family psychoeducation plus standard care versus standard care alone in reducing relapse in schizophrenia

3. A cross-sectional neurophysiological study of P300 ERP latency differences in chronic versus first-episode psychosis

4. A retrospective cohort analysis of metabolic syndrome incidence in patients on second-generation antipsychotics: risperidone versus olanzapine

5. An in vitro assay of neuronal cell culture treated with patient-derived serum to assess complement activation in psychosis

6. A case-control evaluation of cannabis use patterns and age of onset in early-onset versus late-onset schizophrenia

7. A methodological validation of smartphone-based Ecological Momentary Assessment (EMA) for monitoring psychotic symptom fluctuations

8. A systematic review and meta-analysis of cognitive remediation therapy efficacy in improving functional outcomes in schizophrenia

9. An in silico pharmacogenomic study predicting antipsychotic response based on CYP2D6 genotype in psychotic disorders

10. A narrative review of long-acting injectable antipsychotics: adherence, relapse prevention, and real-world effectiveness

3. Anxiety & Trauma-Related Disorders

1. A prospective cohort study of heart rate variability biofeedback efficacy in reducing generalized anxiety symptoms in medical students

2. A randomized double-blind trial comparing virtual reality exposure therapy versus imaginal exposure in combat-related PTSD: symptom severity and drop-out rates

3. A cross-sectional evaluation of amygdala functional connectivity using resting-state fMRI in social anxiety disorder versus controls

4. A retrospective cohort study of antidepressant versus benzodiazepine long-term use and risk of dependency in panic disorder patients

5. An in vitro inflammatory marker assay (IL-6, CRP) in trauma survivors with and without PTSD

6. A case-control genetic association study of FKBP5 polymorphisms in individuals with complex PTSD versus trauma-exposed controls

7. A methodological validation of the GAD-7 scale for anxiety screening in non-English-speaking populations

8. A systematic review and meta-analysis of mindfulness-based stress reduction effectiveness in generalized anxiety disorder

9. An in silico docking study of benzodiazepine receptor modulators for novel anxiolytic development

10. A narrative review of emerging neurobiological treatments (ketamine, MDMA-assisted therapy) in PTSD

4. Child & Adolescent Psychiatry

1. A prospective cohort study of early life adversity and salivary cortisol patterns predicting adolescent depression onset

2. A randomized controlled trial of parent–child interaction therapy versus standard care in reducing disruptive behaviors in preschoolers

3. A cross-sectional evaluation of executive function deficits using CANTAB in ADHD versus typically developing children

4. A retrospective cohort analysis of long-term metabolic outcomes in adolescents treated with stimulants for ADHD

5. An in vitro assessment of microRNA expression in peripheral blood from children with autism spectrum disorder

6. A case-control study of sleep architecture abnormalities on polysomnography in children with anxiety disorders versus controls

7. A methodological validation of the Strengths and Difficulties Questionnaire (SDQ) in school-based mental health screening

8. A systematic review and meta-analysis of omega-3 fatty acid supplementation in improving ASD symptoms in children

9. An in silico epigenetic modulation analysis of candidate genes implicated in adolescent bipolar disorder

10. A narrative review of school-based mental health interventions: implementation and outcomes in low-resource settings

5. Geriatric Psychiatry

1. A prospective observational study of mild cognitive impairment progression to dementia: role of serum neurofilament light chain as a biomarker

2. A randomized double-blind trial of SSRIs versus SNRIs for late-life depression: efficacy, tolerability, and quality-of-life measures

3. A cross-sectional assessment of frailty, polypharmacy, and falls risk among community-dwelling older adults with depression

4. A retrospective cohort analysis of antipsychotic prescribing patterns and mortality risk in elderly patients with dementia-related psychosis

5. An in vitro amyloid-beta aggregation assay with plasma from Alzheimer’s disease versus control participants

6. A case-control evaluation of APOE ε4 allele frequency in early-onset versus late-onset Alzheimer’s disease

7. A methodological validation of telepsychiatry cognitive assessments in older adults with mobility limitations

8. A systematic review and meta-analysis of cognitive stimulation therapy effectiveness in mild to moderate dementia

9. An in silico network analysis of neuroinflammatory pathways in aging brains for therapeutic target identification

10. A narrative review of non-pharmacological interventions (music therapy, reminiscence) in improving mental health of older adults

6. Substance Use Disorders & Addiction

1. A prospective cohort study of buprenorphine versus methadone maintenance: retention rates and quality-of-life outcomes in opioid use disorder

2. A randomized controlled trial of contingency management versus cognitive behavioral therapy in stimulant use disorders: abstinence rates

3. A cross-sectional evaluation of cortical gray matter volume changes on MRI in chronic alcohol-dependent patients vs. social drinkers

4. A retrospective cohort analysis of overdose risk factors in prescription opioid users: demographic and clinical predictors

5. An in vitro assay of CRISPR-based gene editing on mu-opioid receptor expression in neuronal cell lines

6. A case-control genetic association study of DRD2 polymorphisms in nicotine dependence versus non-dependent smokers

7. A methodological validation of smartphone app–based ecological momentary assessment for craving monitoring in SUD

8. A systematic review and meta-analysis of pharmacotherapy (naltrexone, acamprosate) efficacy in alcohol use disorder

9. An in silico pharmacokinetic–pharmacodynamic model of extended-release naltrexone in opioid relapse prevention

10. A narrative review of emerging neuromodulation treatments (tDCS, DBS) in substance use disorders

7. Biological Psychiatry & Neuroimaging

1. A prospective functional MRI study of default mode network connectivity changes in depression before and after ECT

2. A cross-sectional PET imaging analysis of dopamine D2 receptor availability in schizophrenia versus healthy controls

3. A retrospective cohort correlation of serum inflammatory markers (CRP, IL-6) with hippocampal volume in major depressive disorder

4. An in vitro assay of neuronal differentiation in iPSC-derived neurons from bipolar disorder patients

5. A case-control study of gut microbiome composition in patients with anxiety disorders versus matched controls using 16S rRNA sequencing

6. A methodological validation of resting-state EEG biomarkers for early detection of psychosis

7. A systematic review and meta-analysis of gray matter changes in PTSD: voxel-based morphometry studies

8. An in silico structural modeling of NMDA receptor subunits in schizophrenia for targeted drug design

9. A pilot clinical trial of transcranial ultrasound stimulation for modulation of prefrontal cortex activity in depression

10. A narrative review of blood-based biomarkers for diagnosis and prognosis in psychiatric disorders

8. Psychotherapy & Psychosocial Interventions

1. A randomized controlled trial of cognitive analytic therapy versus dialectical behavior therapy in borderline personality disorder: symptom reduction and emotion regulation

2. A prospective cohort study of group interpersonal psychotherapy efficacy in reducing antenatal depression symptoms in low-resource settings

3. A cross-sectional survey of therapeutic alliance measures and treatment adherence in outpatient psychotherapy clients

4. A retrospective cohort analysis of long-term outcomes in trauma-focused CBT versus EMDR for childhood trauma survivors

5. An in vitro stress hormone (cortisol) assay in saliva before and after mindfulness-based stress reduction sessions

6. A case-control evaluation of family support scales and relapse rates in patients undergoing addiction rehabilitation

7. A methodological validation of virtual reality–based social skills training modules for autism spectrum disorder

8. A systematic review and meta-analysis of e-mental health interventions (apps, online CBT) effectiveness in anxiety and depression

9. An in silico sentiment analysis of online peer support forums for mental health: themes and emotional tone

10. A narrative review of cultural adaptations of psychotherapeutic modalities in diverse populations

9. Forensic & Legal Psychiatry

1. A cross-sectional study of competency to stand trial evaluations: inter-rater reliability between forensic psychiatrists

2. A prospective cohort study of recidivism rates in violent offenders with severe mental illness following court-ordered community treatment

3. A retrospective case series of assessment and management of fitness to plead in defendants with intellectual disability

4. An in vitro assessment of psychophysiological measures (polygraph, P300) in malingering detection among criminal defendants

5. A case-control analysis of structural brain differences on MRI between parricide offenders and matched violent offenders

6. A methodological validation of the MacArthur Competence Assessment Tool–Criminal Adjudication (MacCAT-CA) in local languages

7. A systematic review and meta-analysis of risk assessment tools (HCR-20, VRAG) predictive validity for violent reoffending

8. An in silico modeling study of sentencing outcomes based on mental health mitigation factors in legal databases

9. A pilot evaluation of tele-forensic psychiatry consultations for court hearings: feasibility and stakeholder satisfaction

10. A narrative review of ethical challenges in forensic psychiatry practice: confidentiality, dual obligations, and consent

10. Recent Advances in Psychiatry

1. A scoping review of artificial intelligence–driven predictive models for suicide risk assessment: accuracy and ethical considerations

2. A prospective pilot study of psychedelic-assisted psychotherapy (psilocybin) in treatment-resistant depression: safety and feasibility

3. A methodological assessment of digital phenotyping using smartphone sensor data for early detection of mood episode relapse

4. An in vitro validation of extracellular vesicle–based biomarkers for bipolar disorder diagnosis from patient plasma

5. An in silico multi-omics integration to identify endophenotypes of schizophrenia for personalized medicine approaches

6. A systematic review and meta-analysis of ketamine-assisted psychotherapy for PTSD: efficacy and adverse events

7. A narrative review of CRISPR-Cas9–based gene-editing prospects for monogenic neuropsychiatric disorders

8. A pilot clinical trial of closed-loop deep brain stimulation targeting subcallosal cingulate in severe treatment-resistant depression

9. A retrospective data-mining analysis of electronic health record big data to predict antipsychotic side-effect profiles

10. A narrative review of virtual reality–based interventions for psychosis: technological advancements and clinical outcomes