Neurology Thesis Topics

Neurology Thesis Topics

Neurology deals with diseases of the brain, spinal cord, peripheral nerves and muscles, including stroke, epilepsy, movement disorders, demyelinating diseases and neuromuscular syndromes. This page lists 100 detailed, practical Neurology thesis topics designed for DM Neurology residents in India and trainees in Gulf Cooperation Council countries (UAE, Saudi Arabia, Qatar, Oman, Kuwait, Bahrain), including Arab Board Neurology and Saudi Commission fellowship programmes.

The titles are search-optimised for Neurology thesis topics, DM Neurology dissertation topics India, GCC neurology research ideas, Arab Board neurology project titles, stroke research topics and epilepsy research projects. Most topics are structured as comparative clinical studies, observational cohorts and cross sectional analyses, feasible in tertiary hospitals and teaching institutes across India and GCC.

1. Stroke and Cerebrovascular Diseases

Comparative study of functional outcomes in ischaemic stroke patients treated with intravenous thrombolysis versus conservative therapy in a tertiary-care centre. This project evaluates modified Rankin scale at three months, in-hospital complications and mortality in Indian and GCC populations.
Observational study of risk factor profiles and stroke subtypes using Trial of Org 10172 in Acute Stroke Treatment classification in young adults with ischaemic stroke. The thesis focuses on hypertension, diabetes, dyslipidaemia, smoking, prothrombotic states and cardioembolism.
Comparative study of door-to-needle time before and after implementation of a stroke code protocol in an academic hospital. This research correlates workflow improvement with rates of thrombolysis, haemorrhagic transformation and functional independence.
Cross sectional analysis of carotid and intracranial artery stenosis patterns in patients with transient ischaemic attack and minor stroke. The study uses duplex ultrasonography and magnetic resonance angiography to characterise atherosclerotic burden.
Observational study of functional outcome and mortality in primary intracerebral haemorrhage managed in a neurology service. The thesis analyses haematoma location, volume, blood pressure control and use of prognostic scores.
Comparative study of aspirin versus dual antiplatelet therapy for secondary prevention in minor ischaemic stroke and high-risk transient ischaemic attack. This project evaluates recurrence, bleeding complications and adherence in routine clinical practice.
Cross sectional analysis of stroke in pregnancy and postpartum period in Indian and GCC cohorts. The study examines aetiology, risk factors including pre-eclampsia and outcome for mother and baby.
Observational study of post-stroke depression and anxiety and their impact on rehabilitation outcomes. The thesis uses validated scales to assess mood disturbances and correlation with disability.
Comparative study of outcome in patients undergoing mechanical thrombectomy under general anaesthesia versus conscious sedation where both approaches are used. This research evaluates recanalisation rates, symptomatic haemorrhage and 90-day functional status.
Cross sectional analysis of adherence to evidence-based acute stroke management guidelines in a tertiary neurology unit. The project assesses documentation of stroke scales, early mobilisation, dysphagia screening and secondary prevention.

2. Epilepsy and Seizure Disorders

Comparative study of levetiracetam versus valproate as initial monotherapy in newly diagnosed focal epilepsy in adults. This thesis evaluates seizure control, adverse effects, weight changes and quality of life over one year.
Observational study of adherence to antiepileptic drugs and its determinants in patients with chronic epilepsy attending a neurology clinic. The project investigates socio-economic status, perception of illness, polytherapy and side effects.
Cross sectional analysis of electroencephalography abnormalities in first unprovoked seizure and their predictive value for recurrence. This research categorises epileptiform discharges and background abnormalities and follows patients longitudinally.
Comparative study of seizure outcome and cognitive profile in patients with mesial temporal lobe epilepsy with and without hippocampal sclerosis on magnetic resonance imaging. The thesis evaluates memory impairment, psychiatric comorbidities and response to drug therapy.
Observational study of stigma, employment limitations and marital issues in adults with long-standing epilepsy in India and GCC countries. The project uses structured questionnaires to assess social and cultural impact.
Comparative study of different antiepileptic drug regimens in focal status epilepticus where standard protocols are followed. This research examines seizure termination times, need for intensive care admission and neurological sequelae.
Cross sectional analysis of psychogenic non-epileptic seizures diagnosed by video electroencephalography monitoring. The thesis reviews psychiatric comorbidities, precipitating factors and health-care utilisation.
Observational study of seizure control and teratogenic outcomes in women with epilepsy on antiepileptic drug therapy during pregnancy. The project evaluates seizure frequency, foetal malformations and perinatal complications.
Comparative study of quality of life in patients with controlled versus drug-resistant epilepsy. The research uses validated quality-of-life instruments and measures depression and anxiety.
Cross sectional analysis of antiepileptic drug adverse effect profiles in an outpatient epilepsy cohort. The thesis documents weight gain, cognitive slowing, osteoporosis and cosmetic effects.

3. Neuromuscular Disorders and Electrophysiology

Observational study of clinical and electrophysiological patterns in Guillain–Barré Syndrome in a tertiary neurology centre. The project describes subtypes, need for mechanical ventilation and short-term outcomes.
Comparative study of intravenous immunoglobulin versus plasmapheresis in the treatment of Guillain–Barré Syndrome where both modalities are available. This research evaluates functional recovery, intensive care unit stay and complications.
Cross sectional analysis of chronic inflammatory demyelinating polyradiculoneuropathy and its treatment responses in routine practice. The thesis assesses steroid, intravenous immunoglobulin and immunosuppressant outcomes.
Observational study of hereditary neuropathies in adults and children with progressive distal weakness. The project analyses nerve conduction patterns, genetic testing where feasible and disability.
Comparative study of nerve conduction and electromyography parameters in diabetic versus non-diabetic length-dependent polyneuropathy. This research correlates glycaemic control with severity of electrophysiological abnormalities.
Cross sectional analysis of myasthenia gravis: clinical spectrum, antibody status and treatment outcomes. The thesis evaluates ocular versus generalised disease, thymic pathology and crisis episodes.
Observational study of inflammatory myopathies and correlation of clinical findings with muscle biopsy and electromyography. The project reviews treatment responses to immunosuppressive regimens.
Comparative study of functional outcome and survival in motor neuron disease patients receiving non-invasive ventilation versus standard care. This research evaluates respiratory parameters, quality of life and caregiver burden.
Cross sectional analysis of neuromuscular junction disorders due to drugs and toxins in emergency neurology. The thesis documents causative agents, electrophysiological features and recovery profiles.
Observational study of autonomic function testing in peripheral neuropathies and its association with cardiovascular risk. The project uses heart rate variability and blood pressure response tests to identify dysautonomia.

4. Movement Disorders

Comparative study of levodopa-based therapy versus dopamine agonist–based initial therapy in early Parkinson’s disease. This thesis evaluates motor fluctuations, dyskinesias, non-motor symptoms and quality of life.
Observational study of non-motor symptoms in Parkinson’s disease and their correlation with disease severity. The project assesses sleep disturbance, depression, autonomic symptoms and cognitive decline.
Cross sectional analysis of essential tremor and Parkinsonian tremor using clinical rating scales and neurophysiological tests where available. The research identifies distinguishing features and functional impact.
Comparative study of botulinum toxin therapy versus oral medications in focal dystonias such as cervical dystonia and blepharospasm. The thesis evaluates symptom control, adverse effects and patient satisfaction.
Observational study of gait and balance disorders in elderly patients attending a movement disorder clinic. The project examines falls, fear of falling and association with polypharmacy.
Cross sectional analysis of functional movement disorders: clinical characteristics, psychiatric comorbidities and precipitating events. The thesis describes diagnostic challenges and response to multidisciplinary management.
Observational study of deep brain stimulation candidates with Parkinson’s disease in an Indian or GCC centre. The project assesses selection criteria, preoperative assessment and baseline quality-of-life scores.
Comparative study of different rating scales for assessment of motor symptoms in Parkinson’s disease and their inter-rater reliability. This research evaluates Unified Parkinson’s Disease Rating Scale against simplified tools used in busy clinics.
Cross sectional analysis of drug-induced movement disorders including tardive dyskinesia and antipsychotic-induced parkinsonism. The thesis documents offending drugs, duration of exposure and reversibility.
Observational study of quality of life and caregiver burden in advanced Parkinson’s disease. The project uses standardised questionnaires to assess physical, emotional and social domains.

5. Demyelinating Diseases and Neuroimmunology

Observational study of multiple sclerosis and clinically isolated syndrome spectrum in an Indian or GCC neurology clinic. The project evaluates demographic profile, relapse rate, disability and imaging patterns.
Comparative study of relapse rates and disability progression in patients receiving different disease-modifying therapies for multiple sclerosis where available. This research assesses adherence, side effects and radiological activity.
Cross sectional analysis of neuromyelitis optica spectrum disorders and aquaporin-4 antibody positivity. The thesis reviews clinical features, relapse patterns and response to immunotherapy.
Observational study of myelin oligodendrocyte glycoprotein antibody–associated disorders in paediatric and adult populations. The project describes optic neuritis, encephalitis and transverse myelitis presentations.
Comparative study of acute disseminated encephalomyelitis versus first attack of multiple sclerosis in children. This research evaluates clinical course, imaging changes and outcome at one year.
Cross sectional analysis of autoimmune encephalitis cases and antibody profile where testing is available. The thesis documents clinical features, seizure burden and treatment response.
Observational study of central nervous system involvement in systemic autoimmune diseases such as systemic lupus erythematosus and Sjögren syndrome. The project evaluates imaging, cerebrospinal fluid findings and long-term disability.
Comparative study of high-dose intravenous methylprednisolone versus plasmapheresis in severe demyelinating attacks. This research assesses neurological recovery, relapse prevention and side effects.
Cross sectional analysis of vaccination status and infection risk in patients on chronic immunosuppressive therapy for neuroimmunological disorders. The thesis evaluates adherence to preventive guidelines and infection episodes.
Observational study of quality of life and employment status in patients with chronic demyelinating disorders. The project explores fatigue, depression and social participation.

6. Headache Disorders and Pain Neurology

Cross sectional study of migraine prevalence and trigger factors among medical students or hospital staff in an Indian or GCC setting. The thesis examines impact on productivity, sleep and quality of life.
Comparative study of prophylactic therapies such as beta-blockers versus topiramate in episodic migraine. This research evaluates reduction in headache days, side effects and patient satisfaction.
Observational study of chronic daily headache and medication overuse patterns in a neurology outpatient clinic. The project analyses over-the-counter and prescription analgesic misuse.
Cross sectional analysis of tension-type headache and associated psychological stress, anxiety and depression. The thesis uses validated mental health scales alongside headache questionnaires.
Comparative study of onabotulinumtoxinA injections versus conventional preventive therapy in chronic migraine where facility is available. This research evaluates headache frequency, disability scores and adverse effects.
Observational study of cluster headache and trigeminal autonomic cephalalgias in a tertiary neurology centre. The project describes clinical features, treatment patterns and response.
Cross sectional analysis of primary cough, exertional and sexual headaches in neurology practice. The thesis evaluates precipitating factors and coexistence with other headache disorders.
Observational study of quality of life and disability in migraineurs using Migraine Disability Assessment and Headache Impact Test scores. The project examines occupational and social impairment in India and GCC.
Comparative study of non-pharmacological interventions such as relaxation training and sleep hygiene education plus standard therapy versus standard therapy alone in migraine. This research assesses reduction in headache frequency and medication use.
Cross sectional analysis of red-flag features and secondary headaches detected in a hospital-based headache clinic. The thesis evaluates neuroimaging yield and diagnostic delays.

7. Cognitive Neurology, Dementia and Neurodegenerative Disorders

Cross sectional study of mild cognitive impairment and early dementia in elderly outpatients using standard cognitive screening tools. The thesis examines cardiovascular risk factors, depression and functional status.
Comparative study of Alzheimer’s disease versus vascular dementia on neuropsychological profile and neuroimaging findings. This research evaluates memory, executive dysfunction and white-matter changes.
Observational study of behavioural and psychological symptoms in dementia and their impact on caregiver burden. The project uses caregiver questionnaires and assesses use of psychotropic medications.
Cross sectional analysis of reversible causes of cognitive impairment in patients presenting to a memory clinic. The thesis includes vitamin deficiencies, hypothyroidism, medication effects and depression.
Comparative study of quality of life in patients with Parkinson’s disease dementia versus Alzheimer’s disease. This research evaluates cognitive, motor and neuropsychiatric domains.
Observational study of frontotemporal dementia and its behavioural variants in a tertiary neurology service. The project examines age at onset, genetic testing when feasible and progression.
Cross sectional analysis of caregiver stress, coping strategies and support needs in dementia care. The thesis evaluates support groups, respite services and family dynamics in India and GCC.
Observational study of subjective cognitive decline and its association with mood disorders and lifestyle factors. The project explores exercise, diet, sleep and anxiety.
Comparative study of different cognitive screening tools such as Mini–Mental State Examination and Montreal Cognitive Assessment in diverse educational backgrounds. This research evaluates sensitivity and specificity for early cognitive impairment.
Cross sectional analysis of advance care planning awareness and preferences in patients with dementia and their families. The thesis investigates cultural and religious influences in India and GCC.

8. Neuro-Intensive Care and Neurological Emergencies

Observational study of clinical profile and outcome of patients admitted to a dedicated neurological intensive care unit. The project records indications such as stroke, status epilepticus, encephalitis and neuromuscular respiratory failure.
Comparative study of protocol-based management versus usual care in status epilepticus. This research evaluates time to seizure control, escalation to anaesthesia and functional outcome.
Cross sectional analysis of meningitis and encephalitis cases in a tertiary hospital neurology service. The thesis examines aetiology, cerebrospinal fluid findings, imaging and mortality.
Observational study of ventilator-associated complications in neurology patients requiring prolonged mechanical ventilation. The project assesses pneumonia, delirium and neuromuscular weakness.
Comparative study of outcome prediction scores in neurocritical care patients, such as Acute Physiology and Chronic Health Evaluation and Sequential Organ Failure Assessment. This research evaluates discrimination and calibration in Indian or GCC cohorts.
Cross sectional analysis of electrolyte and metabolic abnormalities in neurological emergencies and their effect on seizure threshold and consciousness. The thesis evaluates hyponatraemia, hyperglycaemia and renal dysfunction.
Observational study of in-hospital delays in obtaining neuroimaging for acute neurological emergencies. The project examines logistics, time targets and impact on management decisions.
Comparative study of invasive versus non-invasive ventilation strategies in neuromuscular respiratory failure where both approaches are practised. This research assesses survival, ventilator days and quality of life.
Cross sectional analysis of code stroke and code neurology activation patterns in an academic centre. The thesis evaluates times, appropriateness and outcomes.
Observational study of neurological complications in patients with sepsis treated in intensive care units. The project assesses delirium, neuropathy, myopathy and long-term cognitive impairment.

9. Peripheral Neuropathy and Autonomic Disorders

Cross sectional study of diabetic peripheral neuropathy prevalence and severity in patients attending diabetic clinics. The thesis uses clinical scores and nerve conduction studies to stage neuropathy.
Comparative study of different screening tools for diabetic neuropathy such as monofilament testing, tuning fork and symptom scores. This research evaluates sensitivity and specificity against nerve conduction studies.
Observational study of painful neuropathy and its impact on sleep quality, mood and daily functioning. The project uses pain scales and quality-of-life questionnaires in India and GCC.
Cross sectional analysis of peripheral neuropathy in patients with chronic kidney disease on dialysis. The thesis evaluates electrophysiological findings, duration of dialysis and associated factors.
Comparative study of duloxetine versus pregabalin in painful diabetic neuropathy where both medications are commonly used. This research assesses pain relief, adverse effects and patient preference.
Observational study of autonomic neuropathy using cardiovascular reflex tests in long-standing diabetic patients. The project evaluates association with syncope, resting tachycardia and orthostatic hypotension.
Cross sectional analysis of nutritional and toxic neuropathies including alcohol, chemotherapy and vitamin deficiencies. The thesis describes clinical patterns, electrophysiology and reversibility.
Observational study of small fibre neuropathy diagnosed by quantitative sensory testing or skin biopsy where available. The project correlates burning pain with diagnostic findings.
Comparative study of home-based exercise programmes plus pharmacotherapy versus pharmacotherapy alone in diabetic neuropathy. This research evaluates gait parameters, balance and fall risk.
Cross sectional analysis of idiopathic neuropathy and diagnostic yield of extensive laboratory and imaging workup. The thesis investigates cost-effectiveness and common underlying causes ultimately identified.

10. Pediatric Neurology

Cross sectional study of causes of global developmental delay in children attending a paediatric neurology clinic. The thesis evaluates perinatal insults, genetic syndromes, metabolic disorders and environmental factors.
Observational study of clinical profile and outcome of childhood epilepsy in a tertiary neurology centre. The project examines seizure types, electroencephalography patterns, treatment response and remission rates.
Comparative study of valproate versus levetiracetam as monotherapy in generalised epilepsies of childhood where both drugs are used. This research evaluates seizure control, weight changes and behavioural effects.
Cross sectional analysis of cerebral palsy subtypes and their association with perinatal risk factors. The thesis assesses spastic, dyskinetic and ataxic forms and associated comorbidities.
Observational study of attention-deficit/hyperactivity disorder and learning difficulties in children with epilepsy. The project evaluates school performance, behavioural assessments and effect of antiepileptic drugs.
Cross sectional analysis of paediatric neuromuscular disorders and their diagnostic yield using creatine kinase, electromyography and genetic testing where available. The thesis documents Duchenne muscular dystrophy and other inherited myopathies.
Observational study of headache disorders in school-going children and adolescents in India or GCC regions. The project characterises migraine, tension-type headache and associated triggers.
Comparative study of ketogenic diet versus standard antiepileptic therapy alone in refractory childhood epilepsy where dietary therapy services exist. This research evaluates seizure reduction, tolerability and nutritional effects.
Cross sectional analysis of autism spectrum disorder and associated neurological comorbidities in a paediatric neurology clinic. The thesis assesses epilepsy, sleep disorders and intellectual disability.
Observational study of parental stress and coping mechanisms in families of children with chronic neurological disabilities. The project uses validated questionnaires and examines support systems in India and GCC.
Premium Neurology Thesis Topics Generate Synopsis on Neurology Topics