Gynecological Oncology Thesis Topics

Gynecological Oncology Thesis Topics

Gynecological oncology is a specialized field that focuses on the diagnosis, staging, treatment and long-term follow-up of malignancies of the cervix, ovary, uterus, vulva and vagina. This page offers a curated list of 100 clinically practical and research-oriented gynecological oncology thesis topics designed for MCh Gynecological Oncology, DM Oncology, and superspeciality residents in India, as well as trainees preparing for Arab Board and GCC residency programs.

These thesis ideas include comparative, cross-sectional and observational study designs that reflect the case spectrum of tertiary cancer centres in India, UAE, Saudi Arabia, Qatar, Kuwait, Oman and Bahrain. These titles are structured to support academic publishing, dissertation requirements, and clinical audit objectives for those searching for gynecologic oncology thesis topics, MCh oncology dissertation topics, or GCC gynecologic cancer research ideas.

1. Cervical Cancer

Observational study on clinical presentation, staging patterns and delay in diagnosis among women with cervical cancer in a tertiary cancer centre. This study evaluates sociodemographic factors, symptom duration, stage at diagnosis and determinants of late presentation in Indian and GCC referral settings.
Comparative study of treatment response and toxicity between concurrent chemoradiation protocols in locally advanced cervical cancer. The project compares radiotherapy schedules, chemotherapy regimens, acute toxicity and short-term treatment outcomes in real-world practice.
Cross-sectional analysis of human papillomavirus genotype distribution in women diagnosed with cervical intraepithelial neoplasia and cervical cancer. This study identifies predominant HPV genotypes and correlates genotype patterns with severity of disease and age distribution.
Prospective evaluation of quality of life before and after treatment in women receiving chemoradiation for cervical cancer. The study measures functional, emotional and symptom scales and tracks their evolution across treatment phases.
Observational study on recurrence patterns and survival outcomes in women treated for cervical cancer. This project analyses site of recurrence, timing, salvage treatment and survival, helping identify predictors of poor outcomes.
Study of treatment delays and their impact on disease progression in cervical cancer patients undergoing chemoradiation. The research explores reasons for delays, including logistics and comorbidities, and correlates delays with response and outcomes.
Cross-sectional study of anaemia, nutritional status and treatment-related complications in women undergoing cervical cancer therapy. This thesis examines baseline haemoglobin, body mass index and micronutrient status and their influence on toxicity and tolerance.
Comparative analysis of open versus minimally invasive radical hysterectomy outcomes in early-stage cervical cancer. The study evaluates operative time, complications, lymph node yield and early oncologic outcomes across surgical approaches.
Observational study on adherence to follow-up protocols and barriers to routine surveillance among cervical cancer survivors. This research identifies sociodemographic, psychological and systemic barriers affecting long-term follow-up compliance.
Study of fertility-preserving treatment outcomes in young women with early-stage cervical cancer. The thesis assesses oncologic safety, reproductive outcomes and quality of life after fertility-sparing procedures.

2. Ovarian Cancer

Observational study on clinical characteristics and stage distribution of epithelial ovarian cancer at initial presentation. This project explores subtype patterns, tumour burden, ascites and diagnostic pathways in ovarian cancer patients.
Comparative study of neoadjuvant chemotherapy versus primary debulking surgery in advanced epithelial ovarian cancer. The research compares cytoreduction rates, surgical morbidity, chemotherapy response and short-term survival.
Cross-sectional evaluation of CA-125, HE4 and ROMA score in predicting malignancy in adnexal masses. This thesis assesses diagnostic performance of biomarkers and their correlation with imaging and histopathology.
Study of patterns of recurrence and survival in women treated for high-grade serous ovarian carcinoma. The project evaluates timing of recurrence, associated risk factors and post-recurrence treatment outcomes.
Observational study of germ cell and sex-cord stromal ovarian tumours: clinical profile and treatment outcomes. This thesis documents presentation, biomarkers, fertility preservation decisions and survival outcomes in non-epithelial tumours.
Study of chemotherapy-related toxicity and tolerance patterns in women receiving paclitaxel-based regimens for ovarian cancer. This research tracks neuropathy, myelosuppression and hospitalisation rates and correlates them with age, performance status and comorbidities.
Observational analysis of quality of life and functional status in ovarian cancer patients undergoing chemotherapy. The study captures changes in physical, emotional and social functioning across treatment cycles.
Study of genetic risk assessment practices for hereditary ovarian cancer where testing is available. This project documents referral patterns, uptake of genetic counselling, family history and outcomes of testing.
Cross-sectional study of tumour marker kinetics as predictors of treatment response in ovarian cancer. The thesis assesses early decline in CA-125 and its association with radiologic and survival outcomes.
Study of venous thromboembolism risk factors and incidence in ovarian cancer patients undergoing treatment. This research identifies baseline risk factors, timing of events and prevention practices in cancer-associated thrombosis.

3. Endometrial Cancer

Cross-sectional study of risk factors and clinical profile of women diagnosed with endometrial cancer. This thesis evaluates obesity, diabetes, hypertension, reproductive history and symptom patterns in affected women.
Comparative study of sentinel lymph node mapping versus systematic lymphadenectomy in early-stage endometrial cancer. The project compares detection rates, complications, node positivity and operative time.
Observational study on accuracy of ultrasound and endometrial thickness in predicting endometrial malignancy. This research correlates imaging findings with biopsy results and evaluates predictive cut-off values.
Study of prognostic factors influencing survival outcomes in endometrial carcinoma. The thesis analyses grade, depth of myometrial invasion, lymphovascular invasion and tumour subtype.
Study of recurrence patterns in endometrial cancer treated with surgery and adjuvant therapy. This project assesses local versus distant recurrence, timing and post-recurrence survival.
Observational study of chemotherapy-related toxicity in advanced or recurrent endometrial carcinoma. The study documents haematologic, gastrointestinal and neuropathic toxicities and identifies risk predictors.
Cross-sectional analysis of hormone receptor status and clinicopathological correlations in endometrial cancer. This thesis evaluates estrogen and progesterone receptor expression and their associations with tumour behaviour.
Study of minimally invasive surgery outcomes in early-stage endometrial cancer. The research compares operative parameters, complications, lymph node yield and recovery patterns.
Study of patient adherence to surveillance after treatment for endometrial cancer. This project identifies factors influencing compliance and evaluates recurrence detection patterns.
Observational study of coexisting metabolic disorders in endometrial cancer patients and their treatment implications. This research examines diabetes, dyslipidaemia and obesity and their impact on treatment planning and outcomes.

4. Vulvar and Vaginal Cancers

Cross-sectional study of clinical presentation and risk factors of vulvar cancer in a tertiary oncology centre. This thesis evaluates age, symptoms, HPV status and comorbidities associated with vulvar malignancies.
Study of surgical outcomes and complications in women undergoing radical vulvectomy and groin node dissection. The project assesses wound complications, lymphoedema and early oncologic outcomes.
Observational study on patterns of recurrence in vulvar cancer and predictors of poor prognosis. This research analyses local versus distant recurrence, timing and risk factors influencing survival.
Study of human papillomavirus involvement in vaginal intraepithelial neoplasia and vaginal carcinoma. The thesis correlates HPV positivity with grade of dysplasia and tumour behaviour.
Study of chemoradiation tolerance in women with locally advanced vaginal cancer. This research examines treatment interruptions, toxicity patterns and short-term disease response.
Cross-sectional study of sexual health and quality of life in survivors of vulvar and vaginal cancers. The project assesses body image, sexual function and psychosocial outcomes after treatment.
Study of diagnostic delays and health-seeking behaviour in women with vulvar cancer. This thesis evaluates early symptoms, stigma, access to care and factors contributing to late diagnosis.
Observational analysis of HPV vaccination awareness among women treated for vulvar or vaginal neoplasia. The research assesses knowledge gaps and vaccination uptake patterns.
Study of lymph node metastasis patterns in vulvar cancer and their prognostic implications. The thesis evaluates the frequency and distribution of metastasis and its impact on survival.
Study of patient-reported outcomes after reconstruction for vulvar cancer surgery. This project documents healing, satisfaction and functional outcomes following reconstructive procedures.

5. Gestational Trophoblastic Disease

Cross-sectional study of epidemiology and clinical presentation of hydatidiform mole in a tertiary hospital. This thesis evaluates age distribution, risk factors, ultrasound findings and baseline β-hCG values.
Study of treatment response and remission rates in women with low-risk gestational trophoblastic neoplasia receiving single-agent chemotherapy. The research examines toxicity, number of cycles required and relapse rates.
Study of high-risk gestational trophoblastic neoplasia: prognostic factors and outcomes with multi-agent chemotherapy. This project evaluates stage, metastatic burden, treatment tolerance and survival outcomes.
Observational study on β-hCG kinetics as a predictor of treatment response in gestational trophoblastic neoplasia. The thesis correlates early fall patterns with response and relapse probability.
Study of fertility and reproductive outcomes after treatment for gestational trophoblastic disease. This research evaluates menstrual recovery, fertility rates and pregnancy outcomes post-therapy.
Cross-sectional analysis of complications associated with evacuation in molar pregnancy. This project documents haemorrhage, infection, persistent disease and need for repeat procedures.
Study of metastatic patterns in gestational trophoblastic neoplasia and their impact on prognosis. The thesis evaluates lung, liver, brain and other metastatic sites and correlates them with outcomes.
Study of patient knowledge and counselling practices regarding contraception after gestational trophoblastic disease. This research identifies gaps in education and counselling after treatment.
Observational study of response to salvage chemotherapy in relapsed gestational trophoblastic neoplasia. This thesis evaluates response rates, toxicity and survival in relapsed disease.
Study of long-term follow-up adherence among women treated for gestational trophoblastic disease. The project identifies barriers to surveillance and relapse detection.

6. Gynecologic Oncology Surgery and Minimally Invasive Techniques

Comparative study of open versus minimally invasive radical hysterectomy for early cervical cancer. The study analyses operative parameters, complications, lymph node yield and short-term oncologic outcomes.
Study of surgical morbidity and postoperative recovery patterns after cytoreductive surgery for ovarian cancer. The thesis evaluates intraoperative blood loss, operative time, bowel resection frequency and postoperative complications.
Observational study on the role of pelvic and para-aortic lymphadenectomy in gynecologic malignancies. This project assesses indications, nodal positivity rates and impact on staging accuracy.
Study of enhanced recovery after surgery protocols in gynecologic oncology procedures. The research analyses compliance, length of stay, analgesia requirements and early complication rates.
Cross-sectional study of intraoperative complications and risk predictors in major gynecologic cancer surgeries. This thesis examines vascular injury, ureteric injury, bleeding and wound complications.
Study of robotic-assisted surgery outcomes in endometrial and cervical cancers where technology is available. The project evaluates operative efficiency, conversion rates and postoperative recovery metrics.
Observational study on surgical decision-making in fertility-preserving procedures for gynecologic cancers. This research addresses eligibility, oncologic safety and patient preferences.
Study of postoperative lymphoedema incidence and functional impact after pelvic lymphadenectomy. The thesis evaluates onset, severity and impact on mobility and quality of life.
Cross-sectional study of blood transfusion practices in gynecologic oncology surgery. This study evaluates triggers for transfusion, perioperative haemoglobin trends and postoperative outcomes.
Study of predictors of suboptimal cytoreduction in advanced ovarian cancer. The project identifies patient factors and tumour characteristics associated with incomplete tumour removal.

7. Chemotherapy, Targeted Therapy and Immunotherapy in Gynecologic Cancers

Observational study of chemotherapy-related acute toxicity in women receiving platinum-based regimens for gynecologic cancers. The project documents haematologic toxicity, neuropathy, gastrointestinal side effects and factors influencing intolerance.
Study of adherence to chemotherapy schedules and the impact of delays on outcomes in ovarian and cervical cancers. This thesis evaluates reasons for treatment interruptions and their correlation with response.
Cross-sectional analysis of targeted therapy use in ovarian cancer where agents such as PARP inhibitors are available. The study examines indications, toxicity patterns and early efficacy.
Study of immunotherapy response patterns in recurrent or metastatic cervical cancer where available. This research evaluates partial response, stable disease and progression patterns in patients receiving immunotherapy.
Observational study of chemotherapy-induced neuropathy in gynecologic cancer patients. The thesis assesses severity, functional impairment and risk factors.
Study of serum biomarkers predicting chemotherapy response in ovarian and endometrial cancers. This project correlates baseline and dynamic marker changes with radiologic response.
Study of nausea, vomiting and supportive care practices in women receiving chemotherapy. This research explores antiemetic protocols and patient-reported symptom burden.
Cross-sectional analysis of financial toxicity and treatment affordability in gynecologic cancer patients. The thesis documents cost burdens and coping strategies related to cancer therapy.
Study of venous access complications in women receiving long-term chemotherapy. The research evaluates catheter-related infections, thrombosis and device failure.
Study of chemotherapy-related alopecia, body image and psychosocial impact in gynecologic oncology patients. This project assesses emotional distress, coping and support needs.

8. Palliative Care, Survivorship and Quality of Life

Cross-sectional study of symptom burden and palliative care needs in advanced gynecologic cancers. This thesis evaluates pain, fatigue, nausea, breathlessness and psychological distress.
Study of advance care planning awareness and preferences among women with gynecologic malignancies. The research explores willingness to discuss end-of-life preferences and barriers to planning.
Observational study of caregiver burden among families of women with advanced gynecologic cancer. This project measures physical, emotional and financial strain on caregivers.
Study of sexual health, intimacy concerns and relationship changes among gynecologic cancer survivors. The thesis evaluates post-treatment sexual dysfunction, body image issues and partner communication.
Cross-sectional study of fear of recurrence and psychological wellbeing among gynecologic cancer survivors. This study assesses anxiety, coping strategies and support needs.
Study of rehabilitation needs and physical function after pelvic cancer treatment. The research evaluates mobility limitations, pelvic floor dysfunction and benefits of rehabilitation.
Study of financial stress and its effect on quality of life in women with gynecologic cancers. This project correlates economic burden with emotional, social and physical wellbeing.
Observational study of follow-up adherence and barriers among long-term survivors of gynecologic cancers. This thesis identifies demographic and psychosocial predictors of compliance with surveillance.
Study of nutrition status, weight changes and sarcopenia in women undergoing treatment for gynecologic cancers. The research evaluates muscle loss, appetite changes and their clinical implications.
Study of spiritual wellbeing and coping mechanisms among women living with advanced gynecologic cancer. This project assesses the role of spirituality, hope and resilience in coping with illness.

9. Screening, Early Detection and Prevention of Gynecologic Cancers

Cross-sectional study of cervical cancer screening awareness and practices among women attending outpatient clinics. This thesis examines screening uptake, knowledge gaps and barriers.
Study of healthcare provider knowledge and practices regarding HPV vaccination. The project evaluates awareness, attitudes and recommendation patterns among clinicians.
Study of VIA (visual inspection with acetic acid) screening outcomes in low-resource settings. This research assesses sensitivity, positivity rates and referral patterns.
Cross-sectional evaluation of endometrial cancer awareness among perimenopausal and postmenopausal women. The thesis identifies misconceptions and late presentation factors.
Study of genital hygiene practices and their association with cervical precancerous lesions. This research explores lifestyle and cultural practices influencing risk.
Study of HPV self-sampling acceptability among women in India and GCC countries. This project evaluates feasibility, comfort and willingness for self-testing.
Cross-sectional study of family history and hereditary risk awareness among women attending oncology clinics. The thesis assesses awareness of BRCA-related cancers and referral patterns for genetic counselling.
Study of screening outcomes in high-risk women attending hereditary cancer clinics. This research evaluates screening adherence and detection rates.
Study of lifestyle factors such as diet, obesity and physical activity in relation to endometrial cancer risk. The thesis examines the association of modifiable behaviours with cancer risk.
Study of community health worker-led cervical cancer awareness programs and their impact. The project measures change in knowledge, attitudes and screening uptake.

10. Fertility Preservation and Reproductive Outcomes

Observational study of fertility-preserving surgery outcomes in early cervical cancer. The research evaluates oncologic safety, menstrual recovery and reproductive outcomes.
Study of fertility after chemotherapy for ovarian and germ-cell tumours. The thesis assesses ovarian reserve markers, menstrual patterns and pregnancy outcomes.
Cross-sectional study of reproductive counselling practices in young women with gynecologic cancers. The project examines timing, content and patient satisfaction with counselling.
Study of ovarian tissue cryopreservation awareness and acceptability among cancer patients. This research evaluates interest, barriers and cultural influences on fertility preservation decisions.
Study of long-term reproductive health issues in survivors of gestational trophoblastic disease. The thesis analyses menstrual health, fertility and pregnancy complications post-treatment.
Observational study of hormone replacement therapy use in young gynecologic cancer survivors post-treatment. The project evaluates safety, adherence and quality-of-life effects.
Study of pregnancy outcomes following conservative management of endometrial hyperplasia where applicable. This research assesses response, recurrence and reproductive results.
Cross-sectional analysis of psychological impact of fertility loss in women undergoing cancer treatment. The thesis evaluates grief, coping strategies and support systems.
Study of decision-making factors influencing fertility preservation choices among women with gynecologic cancers. The research assesses patient values, cultural factors and economic considerations.
Study of reproductive outcomes after treatment for ovarian borderline tumours. This project evaluates fertility-sparing surgery patterns, recurrence and pregnancy outcomes.
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